Mild Cognitive Impairment (MCI) Stage of the Frontotemporal Dementias: Early Diagnosis and Management The mild cognitive impairment (MCI) stage of neurodegenerative diseases refers to an early clinical phase of the disease in which a change has been observed in an individual's cognition or behavior but the person is generally able to maintain independent functioning in daily activities with minimal aids or assistance. At ... Article
Article  |   May 01, 2014
Mild Cognitive Impairment (MCI) Stage of the Frontotemporal Dementias: Early Diagnosis and Management
Author Affiliations & Notes
  • Kimiko Domoto-Reilly
    Frontotemporal Dementia Unit, Department of Neurology, Massachusetts Alzheimer's Disease Research Center, Charlestown, MA
  • Daisy Sapolsky
    Frontotemporal Dementia Unit, Departments of Psychiatry and Speech and Language Pathology, Massachusetts General Hospital, Boston, MA
  • Bradford C. Dickerson
    Frontotemporal Dementia Unit, Departments of Neurology and Psychiatry, Massachusetts Alzheimer's Disease Research Center, Boston, MA
    Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA
  • Disclosure: Financial: Kimiko Domoto-Reilly and Daisy Sapolsky have no financial interests to disclose. Bradford C. Dickerson received a federal grant for this research.
    Disclosure: Financial: Kimiko Domoto-Reilly and Daisy Sapolsky have no financial interests to disclose. Bradford C. Dickerson received a federal grant for this research.×
  • Nonfinancial: Kimiko Domoto-Reilly, Daisy Sapolsky, and Bradford C. Dickerson have no nonfinancial interests to disclose.
    Nonfinancial: Kimiko Domoto-Reilly, Daisy Sapolsky, and Bradford C. Dickerson have no nonfinancial interests to disclose.×
Article Information
Special Populations / Older Adults & Aging / Early Identification & Intervention / Attention, Memory & Executive Functions / Articles
Article   |   May 01, 2014
Mild Cognitive Impairment (MCI) Stage of the Frontotemporal Dementias: Early Diagnosis and Management
SIG 15 Perspectives on Gerontology, May 2014, Vol. 19, 57-64. doi:10.1044/gero19.2.57
SIG 15 Perspectives on Gerontology, May 2014, Vol. 19, 57-64. doi:10.1044/gero19.2.57

The mild cognitive impairment (MCI) stage of neurodegenerative diseases refers to an early clinical phase of the disease in which a change has been observed in an individual's cognition or behavior but the person is generally able to maintain independent functioning in daily activities with minimal aids or assistance. At an early stage of most neurodegenerative diseases, including the Frontotemporal Dementias, it can be very difficult to determine whether a person has symptoms of a progressive illness or is suffering from a condition less likely to progress, or even exhibiting symptoms consistent with normal aging. It is critical to identify individuals with MCI, since people with this clinical syndrome are at elevated risk of progressive cognitive decline. In the case of Primary Progressive Aphasia, a neurodegenerative disease in which speech and/or language abilities are gradually lost, a speech-language pathologist (SLP) may be one of the initial clinical providers in the MCI stage. The SLP is therefore critical in helping to determine whether a change in language abilities is a result of normal aging, a neurodegenerative process, or other etiologies.

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